Kaley Cuoco most recently starred and executive produced the breakout hit comedic thriller The Flight Attendant. Season one of the series was based on the novel of the same name by Chris Bohjalian and told the story of how an entire life can change in one night. Flight attendant Cassie Bowden (Cuoco) wakes up in the wrong hotel, in the wrong bed, with a dead man —and no idea what happened. The series was quickly renewed for a second season, and Cuoco received multiple award nominations, including lead actress nods from the Golden Globe Awards, Screen Actors Guild Awards and Critics Choice Awards, comedy series nominations from the Golden Globes and Critics Choice, and best comedy series ensemble from the Screen Actors Guild Awards.

She is best known to television audiences for her role as Penny on The Big Bang Theory, which signed off in May 2019 after 12 seasons and 279 episodes, making it the longest-running multicamera series in television history.

Cuoco and her Yes, Norman Productions team are developing ideas for original television projects for streaming, cable and broadcast through its overall deal with Warner Bros. Television Group. In addition to producing The Flight Attendant, Yes, Norman currently produces Warner Bros. Animation’s Harley Quinn for HBO Max. Cuoco voices the role of the title character and serves as an executive producer on the half-hour adult animated action-comedy.

Prior to The Big Bang Theory, Cuoco starred as Bridget Hennesy in the series 8 Simple Rules. Her other television credits include a recurring role on Charmed and guest appearances on Complete Savages and Prison Break. She also starred in the cable movies Fat Like Me, Crimes of Fashion and The Hollow, and was seen in the miniseries, 10.5. Her other television movie credits are Alley Cats Strike, Toothless, Attack of the 50Ft Woman, Growing Up Brady, and the miniseries, Dean Koontz's Mr. Murder. Additionally, Cuoco lent her voice to the animated series Brandy and Mr. Whiskersand Loonatics Unleashed. 

Cuoco began her acting career at a young age, appearing in commercials and modeling. Her first TV role was in 1992's Quicksand: No EscapeoppositeDonald Sutherland. She landed her first feature film role at the age of eight in Virtuosity. Her other film credits include Picture Perfect, Can't Be Heaven and Lucky 13. She also appeared on stage in community theater productions of Fiddler on the Roof and Annie.

Cuoco appeared on the big screen in Hop, opposite James Marsden. Additionally, she starred in the independent feature The Last Ride, which played at film festivals across the country.

Cuoco is a gifted tennis player and hikes, runs, rides horses, goes to the gym and spends time with her rescue dogs. She is also involved in several charities including EBMRF, the Humane Society, the Elisabeth Glaser Pediatric AIDS Foundation, Animal Avengers and PETA.

Cuoco currently resides in Los Angeles. Her birth date is November 30

Speaking on: Summit Series: Channing Dungey, Greg Berlanti and Kaley Cuoco